Molecular hydrogen research began gaining major attention with the 2007 Nature Medicine study by Ohsawa et al., demonstrating Hβ's selective antioxidant properties. Since then, over 1,000 peer-reviewed studies have been published across fields including neurology, cardiology, sports medicine, dermatology, and oncology. Research institutions worldwide, including in Japan, Korea, China, the USA, and Europe, continue to investigate Hβ's therapeutic potential.